Anti-PWP2 Antibody

Produced as a rabbit polyclonal IgG and supplied by Antibodies.com at 100 µl, this unconjugated reagent targets the PWP2 protein in human and mouse samples for western blot detection. PWP2 (Periodic Tryptophan Protein 2) is a WD40-repeat component of the Pwp2p-containing subcomplex of the 90S pre-ribosome, where it contributes to early cleavage events in precursor rRNA and small-subunit ribosome biogenesis. Researchers use this reagent to characterize pre-rRNA processing, nucleolar function, and ribosome assembly in cell lysate preparations. Studies in developmental systems have linked PWP2 mutations to craniofacial and cardiac defects, making the antibody useful for tissue-specific expression profiling in mouse models and patient-derived samples. The unconjugated format allows pairing with HRP- or fluorophore-conjugated secondary reagents to support either chemiluminescent or fluorescent western blot readouts.