Anti-PUM1 Antibody

A rabbit polyclonal antibody targeting PUM1 (pumilio RNA binding family member 1), offered by Antibodies.com within the Primary Antibodies category. The reagent is unconjugated, of IgG isotype, and raised in rabbit. It is validated for Western blot (WB), immunohistochemistry (IHC), and immunofluorescence (IF), and shows reactivity with human, mouse, and rat samples.

Manufacturer material associated with this reagent discusses its use in research on invasive breast cancer, where PUM1 expression was examined across publicly available DNA microarray (n = 10,872) and RNA sequencing (n = 4,421) cohorts, alongside immunohistochemistry on samples from 100 patients. The work reports that high PUM1 expression correlates with aggressive tumour features, including high histological grade, high Ki-67 expression, negative hormone receptors, and the triple-negative molecular subtype, and is linked to poorer outcomes. The reagent is cited in 1 publication and is accompanied by 3 scientific validation images.