Anti-PTS Antibody

PTS encodes 6-pyruvoyltetrahydropterin synthase, the enzyme that catalyzes the second committed step in the de novo biosynthesis of tetrahydrobiopterin (BH4), an essential cofactor for phenylalanine hydroxylase, tyrosine hydroxylase, and nitric oxide synthase. This rabbit polyclonal antibody from Antibodies.com is raised against PTS and validated for Western blot and immunofluorescence applications across human, mouse, and rat samples. Supplied as 100 µl of unconjugated antiserum, the reagent supports detection of endogenous PTS expression in cell lysates, tissue cryosections, and cultured cells, with the polyclonal format offering recognition of multiple epitopes on the target protein. Researchers investigating BH4 metabolism, hyperphenylalaninemia, monogenic tetrahydropterin deficiency, or neurotransmitter synthesis pathways can apply this reagent to expression profiling and subcellular co-localization studies, complementing functional work on pterin cofactor regulation.