Anti-PTPRU Antibody

This polyclonal antibody from Antibodies.com targets PTPRU (Protein Tyrosine Phosphatase Receptor Type U), a receptor-type phosphatase that localizes to cell-cell contacts and modulates cadherin-mediated adhesion. Raised in rabbit and supplied as an unconjugated IgG at 200 µl per vial, the reagent is validated for Western blot detection of endogenous PTPRU protein in mouse and rat samples.

PTPRU, also referenced in the literature as PTPλ, is a transmembrane tyrosine phosphatase expressed in epithelial and neural tissues, where it contributes to adherens junction assembly, contact-dependent growth control, and neurite extension. Laboratories studying junction dynamics, cadherin-catenin signaling, or neural development use this reagent to monitor PTPRU levels across cell lines and primary tissue lysates. The rabbit host allows pairing with common anti-rabbit HRP or fluorescent secondary antibodies on Western blot membranes.

Shipped as 200 µl of liquid polyclonal IgG, the antibody is provided unconjugated for direct immunoblotting or custom labeling workflows and is intended for research use only.