Anti-PTPRE Antibody

PTPRE is a receptor-type transmembrane phosphatase whose signaling has been studied in lymphocytes, osteoclasts, and several solid tumour types. Antibodies.com provides this rabbit polyclonal reagent raised against the human PTPRE sequence, supplied as 200 µl of unconjugated IgG in a liquid format suitable for western blot and immunohistochemistry workflows on cell lysates and formalin-fixed paraffin-embedded tissue sections.

The target belongs to the classical protein tyrosine phosphatase family and contributes to regulation of tyrosine phosphorylation during immune receptor activation and bone resorption control. Published studies link altered PTPRE expression to glioblastoma progression and to receptor signalling in breast carcinoma cell models. The antibody detects the full-length receptor band in WB membranes and labels membrane-associated staining patterns in IHC, with reactivity confirmed specifically for the human protein.

Recommended WB dilutions typically range from 1:500 to 1:2000, while IHC on paraffin sections works well between 1:50 and 1:200 depending on antigen retrieval method. Store the vial refrigerated at 4°C for short-term use; for longer intervals, aliquot and freeze at -20°C, avoiding repeated freeze-thaw cycles to preserve antibody activity. This reagent is supplied as a single-use vial intended for research use only and is not validated for diagnostic procedures.