Anti-PTPN7 Antibody

Generated in rabbit hosts, this polyclonal IgG reagent targets PTPN7, a non-receptor protein tyrosine phosphatase also referenced as HEPTP (hematopoietic tyrosine phosphatase). The antibody is supplied unconjugated in a 50 µl volume and validated for western blot detection of the human PTPN7 protein, which migrates near the 40 kDa marker under reducing SDS-PAGE conditions. PTPN7 functions as a negative regulator of MAPK and ERK signaling cascades and is expressed most prominently in hematopoietic lineages, including T lymphocytes, where it modulates activation events downstream of the T-cell receptor. Distributed by Antibodies.com, the reagent is intended for research use only and suits immunoblotting workflows investigating phosphatase-dependent signaling and leukocyte activation in normal and disease-associated cell systems.