Anti-PTPN7 Antibody

This Rabbit polyclonal primary antibody from Antibodies.com targets PTPN7 (Protein Tyrosine Phosphatase Non-Receptor Type 7), also known as HePTP, a cytoplasmic phosphatase that regulates MAPK cascade signaling. It selectively dephosphorylates the activation loop of ERK1/2, p38, and JNK, making it a useful reagent for studying mitogen-dependent signaling in immune cell models and neuronal tissue.

Supplied as 100 µl of unconjugated IgG in a single-use vial, the antibody is validated for western blot workflows and binds the human PTPN7 target. Researchers can use it to track PTPN7 expression and downstream MAPK phosphorylation status in hematopoietic cell lines and primary lymphocyte samples, or to investigate the phosphatase's role in T-cell receptor signaling and inflammatory responses. The polyclonal format increases the chance of recognition across multiple epitopes of the PTPN7 protein.