Anti-PTPN18 Antibody

PTPN18 belongs to the non-receptor class of protein tyrosine phosphatases and modulates signaling cascades that govern cell proliferation, adhesion, and cytoskeletal remodeling. Raised in rabbit against the human PTPN18 immunogen, this polyclonal IgG reagent is unconjugated and supplied as 100 µl of liquid stock, sized for routine immunoblotting workflows and compatible with standard HRP- or fluorophore-conjugated secondary antibodies. Each lot is validated for western blot detection of endogenous PTPN18 in human cell lysates, and the antibody performs well across denaturing SDS-PAGE conditions followed by PVDF or nitrocellulose transfer.

Aliquot upon first use and store at -20 °C in a frost-free freezer; avoid repeated freeze-thaw cycles to preserve antigen-binding activity. Working dilutions between 1:500 and 1:2000 in 5% non-fat milk/TBST are typically sufficient to visualize PTPN18, with the expected band appearing near the predicted molecular weight of approximately 50 kDa. Researchers studying PTPN18-dependent regulation of receptor tyrosine kinase signaling, breast cancer cell motility, and hematopoietic lineage decisions will find this reagent a useful tool. Sourced and quality-controlled by Antibodies.com, the antibody ships with a lot-specific data sheet so each batch's performance can be verified in your own hands.