Anti-PTPN12 Antibody

This polyclonal primary antibody from Antibodies.com targets PTPN12 (Protein Tyrosine Phosphatase Non-Receptor Type 12), a non-receptor tyrosine phosphatase implicated as a tumor suppressor in HER2-driven breast cancer and other solid malignancies. Raised in rabbit and supplied unconjugated in a 100 µl volume, the reagent is validated for Western blot and immunohistochemistry workflows on human samples.

PTPN12 dephosphorylates components of receptor tyrosine kinase signaling, including HER2 and EGFR, and contributes to cytoskeletal remodeling through substrates such as p130Cas. Investigators studying ErbB2 signaling, cancer cell invasion, or phosphatase biology apply this reagent to detect endogenous PTPN12 expression in cell lysates and formalin-fixed tissue sections.

Key attributes: host species Rabbit, clonality polyclonal, conjugate unconjugated, reactivity to Human, intended for research use only. The unconjugated format supports flexible pairing with secondary antibodies and custom chromogenic or fluorescence detection chemistries.