Anti-PTPN1 Antibody

Produced by Antibodies.com as a rabbit polyclonal reagent raised against protein tyrosine phosphatase PTPN1 (also known as PTP1B), this unconjugated primary antibody is supplied in a 100 µl vial and validated for western blot (WB) and immunofluorescence (IF) workflows. PTPN1 is a non-receptor tyrosine phosphatase broadly studied for its role in downregulating insulin and leptin receptor signaling, making it a frequent target in metabolic disease research, including work on type 2 diabetes and obesity. The reagent binds the PTPN1 target in human, mouse, and rat samples, and the polyclonal format increases the likelihood of recognition across multiple epitopes on the full-length protein. The unconjugated configuration lets laboratories pair the primary with their own HRP- or fluorophore-conjugated secondary antibody, so the same vial can be deployed on chemiluminescent western blot membranes and on fluorescence imaging of cultured cells or tissue cryosections. Storage should follow the manufacturer's recommendations, including protection from light and handling in single-use aliquots where possible, to preserve binding activity across repeat freeze-thaw cycles.