Anti-PTPMT1 Antibody

Produced in rabbit and supplied as 100 µl of unconjugated polyclonal IgG, this Antibodies.com reagent targets PTPMT1, a dual-specificity phosphatase anchored to the inner mitochondrial membrane where it dephosphorylates phosphatidylglycerol phosphate during cardiolipin biosynthesis. Validated for Western blot detection of the murine protein, the antibody is appropriate for studies of mitochondrial lipid metabolism, cristae biogenesis, oxidative phosphorylation, and the cardiolipin remodeling implicated in Barth syndrome. Each vial contains affinity-purified antiserum that should be aliquoted upon arrival and stored at -20°C, with repeated freeze-thaw cycles avoided to preserve immunoreactivity. Researchers working on PTPMT1 knock-out phenotypes, phospholipid signaling, or mitochondrial respiratory chain assembly will find this lot consistent with published characterizations of polyclonal anti-PTPMT1 reagents.