Anti-PTP1C Antibody [PTY11] - Identical to Thermo (MA1-26062)

This Mouse monoclonal antibody, clone PTY11, targets Protein Tyrosine Phosphatase 1 C (PTP1C, also known as SHP-1), a cytosolic SH2-containing tyrosine phosphatase encoded by PTPN6 that acts as a negative regulator of signaling cascades in hematopoietic lineages. Antibodies.com supplies the reagent in a 100 µg lyophilised vial as an unconjugated IgG1, intended for reconstitution in standard assay buffers.

The antibody is validated for ELISA, Western blot, and immunocytochemistry applications and is reactive with human samples. Because PTP1C functions as a key modulator of JAK/STAT and B-cell receptor signaling, the reagent is commonly used to profile phosphatase expression in immune cell lysates, primary lymphocytes, and cultured hematopoietic lines by Western blot, and to map the subcellular localisation of PTP1C in fixed cell preparations by immunocytochemistry. The lyophilised format should be stored refrigerated; reconstituted material is intended for short-term laboratory use.