Anti-PTP1C Antibody [PTY10] - Identical to Thermo (MA1-21486)

PTP1C, also known as SHP-1, is a Src homology 2 domain-containing protein tyrosine phosphatase that acts as a negative regulator of signaling cascades in hematopoietic cell lineages. This mouse monoclonal antibody, clone PTY10, specifically recognizes the human PTP1C protein and is supplied by Antibodies.com as a lyophilised preparation in a 100 µg vial format.

The unconjugated IgG2a reagent is validated for ELISA, western blot, and immunocytochemistry (ICC) applications, supporting studies of phosphatase expression in immune cell signaling, lymphoma research, and hematopoietic differentiation models. Researchers deploy it to probe tyrosine phosphorylation events downstream of cytokine receptors, B-cell receptor signaling, and integrin-mediated adhesion pathways.

Reconstitution calls for resuspension in sterile PBS or deionized water, after which the antibody can be stored refrigerated for routine short-term use. For long-term storage, aliquot and freeze at -20 °C to preserve activity across repeated freeze-thaw cycles. Confirmed reactivity is reported for human samples; performance with non-human species should be evaluated empirically in each laboratory setting.