Anti-PTPζ Antibody

This rabbit-derived polyclonal reagent from Antibodies.com targets PTPε, a receptor-type protein tyrosine phosphatase implicated in neuronal differentiation, immune cell signaling, and negative modulation of insulin receptor activity. The unconjugated IgG fraction is supplied as 100 µl of polyclonal antiserum, suitable for Western blot and ELISA workflows against human, mouse, and rat samples.

The enzyme (gene symbol PTPRE) is a transmembrane phosphatase whose cytoplasmic catalytic domain counterbalances tyrosine kinase cascades, including Erk pathway regulation. Researchers use anti-PTPε antibodies to probe glial signaling, osteoclast differentiation, and receptor-level phosphatase expression in metabolic and neurodevelopmental studies.

Reactivity spans human, mouse, and rat species, supporting cross-species model systems. Host species is rabbit; clonality is polyclonal; the conjugate is unconjugated, leaving the antibody free for downstream labeling with HRP, biotin, or fluorophore tags as the experimental design requires.