Anti-PTMA Antibody

Prothymosin Alpha is a small, intrinsically disordered nuclear polypeptide implicated in chromatin remodeling, cell-cycle progression, and immunomodulation, making its accurate localization valuable across cancer biology and proliferation research. This unconjugated rabbit polyclonal IgG reagent from Antibodies.com binds endogenous human PTMA in immunofluorescence workflows and yields the nuclear-localized signal that characterizes the antigen's known distribution in fixed mammalian cells. The 200 µl liquid aliquot is supplied without any fluorophore or enzyme conjugation, so it can be paired with a researcher-selected secondary for fluorescence imaging or other indirect detection strategies. Confirmed reactivity against human samples supports fluorescence imaging of cultured cells, colocalization studies with proliferation markers, and tumor tissue immunostaining where altered PTMA expression has been linked to disease outcome in head and neck, breast, bladder, and gastric cancers. The reagent is for research use only; aliquoting on first thaw and storage at -20 °C with minimal freeze-thaw cycles preserves polyclonal IgG stability over long-term experiments.