Anti-PTMA Antibody [5A10]

Mouse monoclonal (clone 5A10) antibody directed against human Prothymosin alpha, a small acidic nuclear protein encoded by the PTMA gene that is widely investigated in oncology, cell cycle regulation, and chromatin biology. Supplied by Antibodies.com as 100 µg of lyophilised product, unconjugated and formulated in IgG2a isotype, the reagent is validated for Western blot (WB) and ELISA workflows on human samples.

Prothymosin alpha acts as a transcriptional co-activator, partners with histone chaperones, and modulates apoptosis pathways, with documented overexpression in hepatocellular carcinoma, breast tumours, and several other malignancies. Researchers use the 5A10 clone to monitor endogenous PTMA expression across cell lysates, tissue extracts, and recombinant preparations; the unconjugated format enables downstream coupling to HRP, biotin, or chosen fluorophores for in-house detection assays. The lyophilised vial supports storage at refrigerated temperatures and reconstitution into single-use aliquots that tolerate routine freeze-thaw cycles within ongoing laboratory programmes.