Anti-PTMA Antibody [4A7]

This Mouse monoclonal IgG1 antibody from Antibodies.com targets Prothymosin alpha (PTMA), a highly acidic nuclear protein implicated in chromatin remodeling, cell cycle progression, and inhibition of apoptosis. The 4A7 clone is supplied as a lyophilised 100 µg preparation and is validated for Western blot (WB) and ELISA workflows against human samples. As an unconjugated reagent, it accepts HRP, fluorescent, or biotin-based secondary antibody pairing without modification of the primary.

PTMA is widely studied in oncology, where its elevated expression has been documented in hepatocellular carcinoma, breast cancer, and several hematological malignancies, making this antibody a useful tool for researchers investigating proliferation markers, tumor biology, and nuclear signaling pathways. The antibody recognizes the native human PTMA isoform and is raised in mouse, allowing clear species-specific detection in human cell and tissue lysates. After reconstitution in sterile distilled water, the antibody should be aliquoted to minimize freeze-thaw cycles and preserve binding activity across repeat experiments.

Each lot is produced under standardized hybridoma culture conditions and quality-controlled to ensure consistent batch-to-batch performance, supporting reproducible results across immunoblotting and plate-based immunoassay experiments. Researchers studying transcription regulation, histone acetylation dynamics, or apoptosis-modulating factors will find this PTMA-specific antibody a targeted addition to their antibody panel.