Anti-PTH2R Antibody

Generated in rabbits and affinity-purified, this unconjugated polyclonal IgG reagent from Antibodies.com targets the human parathyroid hormone 2 receptor (PTH2R), a class B G protein-coupled receptor that responds to the ligand TIP39 and is most abundantly expressed in central nervous system neurons, with additional transcripts in kidney and pancreatic tissue.

Validated for Western blot, the antibody is supplied as 100 µl of reagent intended to probe receptor expression, post-translational modification, and downstream cAMP signaling in cell lysates and tissue homogenates. Researchers studying PTH2R function in bone metabolism, nociception, cardiovascular regulation, and neuroendocrine signaling can deploy the antibody in chemiluminescent or fluorescent workflows with HRP- or fluorophore-conjugated secondary reagents.

The product is intended for research use only and is appropriate for in vitro studies of receptor trafficking, ligand binding, and validation of PTH2R knockout or overexpression models in human cell lines.