Anti-PTH / PTHrP-R Antibody

This rabbit polyclonal reagent targets the parathyroid hormone / parathyroid hormone-related peptide receptor (PTH/PTHrP-R), a class B G-protein coupled receptor that mediates PTH and PTHrP actions in bone, kidney, and cartilage. Antibodies.com supplies the antibody in a 100 µl vial as an unconjugated polyclonal, raised in rabbit and reactive against human, mouse, and rat samples. The reagent is validated for Western blot, immunohistochemistry, immunofluorescence, and ELISA workflows, supporting studies of calcium homeostasis, skeletal development, and signaling through the PTH1 receptor.

The target, sometimes designated PTH1R, plays a central role in endocrine regulation of mineral ion balance and chondrocyte differentiation. Researchers commonly use this reagent to characterize receptor expression in tissue sections and to detect endogenous PTH/PTHrP-R by Western blot. Store refrigerated and protect from light to preserve antibody activity across multiple freeze-thaw cycles; aliquot upon first use to limit repeated thawing of the stock vial.