Anti-PTGES2 Antibody

Prostaglandin E synthase 2 (PTGES2) is a glutathione-dependent membrane-associated enzyme that catalyzes the conversion of prostaglandin H2 (PGH2) to prostaglandin E2 (PGE2), a lipid mediator central to inflammation, fever, and pain signaling pathways. Antibodies.com offers this polyclonal primary antibody, raised in rabbit hosts and supplied as an unconjugated IgG preparation for immunoblotting workflows.

Each 200 µl vial contains affinity-purified antiserum in a liquid format. The reagent detects endogenous PTGES2 in mouse samples by western blot, yielding a band near the expected ~41 kDa molecular weight under standard reducing SDS-PAGE conditions. The product's validated reactivity is mouse, providing a specific tool for studies in murine model systems.

Investigators studying eicosanoid biosynthesis, the arachidonic acid cascade, or prostaglandin-mediated signaling use this antibody in murine models to map PTGES2 distribution across tissues and to monitor induced expression in inflammation models. The unconjugated IgG format gives flexibility to pair with HRP-, fluorescent-, or biotinylated-secondary antibodies selected by the investigator.

Store refrigerated; aliquot upon first use to limit freeze-thaw cycles and preserve reagent performance. For research use only.