Anti-PTGER1 Antibody

Raised in rabbit against the human PTGER1 protein, this unconjugated polyclonal antibody recognizes the EP1 subtype of the prostaglandin E2 receptor family. The immunoglobulin is supplied as a 50 µL liquid aliquot in IgG isotype form, ready for direct labeling or downstream detection workflows. The reagent has been validated for Western blot applications on lysates derived from human and mouse samples, where it identifies endogenous receptor expression in tissues such as smooth muscle, kidney, and select neuronal populations.

PTGER1 couples primarily through Gq-type G proteins, raising intracellular calcium upon prostaglandin E2 binding. Researchers rely on Antibodies.com reagents to investigate contractile signaling, inflammatory pain pathways, and phospholipase C activation through this receptor. As an unconjugated primary reagent, the antibody integrates cleanly with HRP-, biotin-, or fluorophore-conjugated secondary reagents, supporting flexible detection strategies in expression profiling and receptor signaling studies.