Anti-PTEN (phospho S370) Antibody

Phosphatase and tensin homolog (PTEN) is one of the most frequently inactivated tumor suppressors in human cancer, and phosphorylation at serine 370 has been linked to regulation of its stability and downstream signaling through the PI3K/AKT axis. This unconjugated rabbit polyclonal IgG reagent from Antibodies.com is raised against PTEN phosphorylated at Ser370 and is validated for Western blot detection of the human protein.

Supplied as a 50 µl liquid aliquot, the antibody supports multiple blot incubations when used at standard dilutions in PBS-based buffers with non-fat milk or BSA blocking. Host species is rabbit, clonality is polyclonal, isotype IgG, and the reagent carries no fluorophore or enzyme label, leaving reporter choice to the end user.

Phospho-S370-specific recognition supports studies of growth-factor- and stress-driven signaling, including downstream effects on AKT, mTOR, and cell-cycle control in cancer, neurodegeneration, and metabolic-disease models. For research use only.