Anti-PTEN (phospho S370) Antibody

Phosphorylation at serine 370 is a regulatory post-translational modification of PTEN (Phosphatase and Tensin homolog), a tumor suppressor lipid phosphatase that antagonizes PI3K/AKT signaling in human cells. This unconjugated rabbit polyclonal IgG reagent, supplied by Antibodies.com, selectively detects PTEN phosphorylated at the S370 residue and is validated for Western blot workflows following SDS-PAGE separation. The 200 µl vial provides ample reagent for multiple immunoblot experiments probing the DNA damage response, CK2 kinase activity, or downstream AKT pathway regulation. Researchers commonly assess S370 phosphorylation status to evaluate PTEN functional regulation in cancer biology and signal transduction studies. The antibody is reactive with human PTEN and intended for research use only. For short-term storage, keep refrigerated; for longer-term storage, freeze in working aliquots to limit repeated freeze-thaw cycles.