Anti-PTEN Antibody

Raised in rabbits against human PTEN, this unconjugated polyclonal IgG reagent detects endogenous PTEN protein across human, mouse, and rat samples in western blot and immunohistochemistry protocols. PTEN is a lipid phosphatase that dephosphorylates PIP3 to PIP2, restraining PI3K/AKT signaling, and its inactivation is a frequent event in prostate, endometrial, and glioblastoma tumors, supporting its broad use in cancer pathway and biomarker studies.

Affinity-purified and supplied by Antibodies.com as a 200 µl liquid vial, the reagent carries a lot-specific concentration suitable for direct detection or downstream labeling with a reporter of choice. Aliquot upon first thaw, store at -20 °C, and avoid repeated freeze-thaw cycles to preserve activity across long-term studies. For research use only.