Anti-PTEN (Ab-380 / 382 / 383) Antibody

This polyclonal antibody from Antibodies.com is raised in rabbit and selectively recognizes PTEN phosphorylated at the C-terminal regulatory sites threonine 380, serine 382, and serine 383 (T380/S382/S383). PTEN is a lipid phosphatase tumor suppressor whose C-terminal tail phosphorylation reduces lipid phosphatase activity and modulates protein stability, making site-specific phospho-detection useful in signaling and cancer research workflows.

Supplied as 100 µL of unconjugated antisera in a single vial, the reagent has been validated for western blot (WB) and immunohistochemistry (IHC). It cross-reacts with mouse and rat PTEN alongside the human target, supporting comparative work across standard laboratory model systems. Store at -20 °C in working aliquots and avoid repeated freeze-thaw cycles to preserve phospho-epitope reactivity. The antibody is intended for research use only and is not cleared for diagnostic or therapeutic applications.