Anti-PTBP1 Antibody

This rabbit-derived polyclonal reagent from Antibodies.com specifically recognizes Polypyrimidine Tract Binding Protein 1 (PTBP1), an approximately 57 kDa RNA-binding protein that regulates pre-mRNA splicing, mRNA stability, translation, and polyadenylation in human cells. The unconjugated antibody is supplied in a 100 µl volume and is validated for Western blot (WB) and immunohistochemistry (IHC) workflows.

PTBP1, also referred to as PTB or hnRNP I, plays documented roles in neuronal differentiation, metabolic gene regulation, and oncogenic reprogramming when its expression is suppressed. Researchers use this reagent to probe PTBP1 abundance in cell lysates by western blot and to localize the protein in fixed tissue sections by immunohistochemistry. The polyclonal format provides broad epitope coverage, useful for detecting full-length PTBP1 alongside any isoforms that may be expressed.

For research use only. Avoid repeated freeze-thaw cycles to preserve antibody activity. Host species: Rabbit. Clonality: Polyclonal. Conjugate: Unconjugated, allowing flexibility with user-supplied fluorophore or enzyme labels. Reactivity has been validated against human samples.