Anti-PTBP1 Antibody

PTBP1 (Polypyrimidine Tract Binding Protein 1), also referred to as hnRNP I, is an approximately 57 kDa RNA-binding protein that regulates alternative pre-mRNA splicing, mRNA stability, translation initiation, and polyadenylation. Researchers turn to this Antibodies.com anti-PTBP1 polyclonal antibody to probe PTBP1 expression and localization across immunoblotting (WB) and immunohistochemistry (IHC) workflows in human, mouse, and rat samples.

This unconjugated rabbit polyclonal reagent is supplied at 1 mg/ml in PBS containing 0.1% sodium azide and 50% glycerol as a cryoprotectant. Each vial contains 100 µl of antibody stock suitable for probing whole-cell lysates, tissue sections, and nuclear or cytoplasmic fractions where PTBP1 acts as a splicing regulator and translation modulator. The antibody recognizes the major ~57 kDa PTBP1 isoform and has been used in studies of neuronal differentiation, stress-granule biology, and cancer metabolism.

Store aliquots at -20 °C and avoid repeated freeze-thaw cycles. The polyclonal Rabbit host reagent and broad species reactivity to Human, Mouse, and Rat support comparative expression studies and cross-species validation experiments. The unconjugated format keeps the antibody flexible for downstream labeling with HRP, fluorophore, or biotin conjugates chosen by the user.