Anti-PSMD5 Antibody

Raised in rabbit against the 26S proteasome non-ATPase regulatory subunit 5, this unconjugated polyclonal IgG Primary Antibody from Antibodies.com targets PSMD5, an integral component of the 19S regulatory cap that recognizes polyubiquitinated substrates destined for proteasomal degradation. The reagent is supplied as a 50 µl vial and is validated for Western blot and immunohistochemistry workflows, supporting detection of the endogenous PSMD5 protein in tissue sections and whole-cell lysates.

Reactivity has been confirmed against human, mouse, and rat samples, making the antibody useful for comparative studies across species in cell cycle regulation, stress response, and cancer biology research where proteasome function is under investigation. For immunohistochemistry, antigen retrieval and peroxidase or fluorescence-based detection systems are compatible with the unconjugated format, while Western blot applications benefit from standard chemiluminescent substrates following SDS-PAGE separation of cell extracts.

Aliquot the reagent upon receipt and minimize freeze-thaw cycles to preserve antibody titer across multiple experiments. Brief handling notes such as gentle centrifugation before opening and protection of the vial from contamination help maintain consistent performance in routine immunoblotting and tissue-staining applications.