Anti-PSMD3 Antibody

PSMD3 encodes a non-ATPase regulatory subunit of the 26S proteasome, the multi-subunit complex responsible for ubiquitin-dependent protein degradation in eukaryotic cells. This unconjugated rabbit polyclonal antibody from Antibodies.com recognizes the human PSMD3 protein and is validated for Western blot and immunohistochemistry workflows. Researchers investigating proteasome assembly, antigen processing for MHC class I presentation, cell cycle regulation, and NF-κB signaling pathways commonly use anti-PSMD3 reagents to characterize the 19S regulatory particle lid subcomplex. Each vial contains 100 µL of polyclonal antiserum raised in rabbit hosts, supplied in a format ready for standard immunodetection buffers. Storage at -20 °C in small aliquots helps preserve reactivity across multiple freeze-thaw cycles. The reagent binds human PSMD3 and has been applied to studies of proteasome assembly, misfolded-protein clearance, and cancer cell line characterization.