Anti-PSMC5 Antibody

PSMC5, also called 26S proteasome regulatory subunit 6A or SUG1, operates as an ATPase within the 19S regulatory particle that powers ubiquitin-dependent substrate turnover by the 26S proteasome. The rabbit polyclonal antibody from Antibodies.com was raised against conserved epitopes and cross-reacts with human, mouse, and rat orthologues.

Each vial provides 100 µl of antibody at 1 mg/ml in PBS with 0.1% sodium azide and 50% glycerol as cryoprotectant, supplied unconjugated for direct labeling or secondary detection workflows. Validated applications include Western blot analysis of PSMC5 expression in cell lysates, immunohistochemistry on paraformaldehyde-fixed tissue sections to map proteasomal distribution, and immunofluorescence staining of cultured cells for subcellular localization. Researchers studying proteostasis, transcription factor degradation, ER-associated degradation, and stress signaling pathways can use this reagent to monitor subunit assembly and abundance. Aliquot upon arrival and store at -20 °C to minimize freeze-thaw exposure of the glycerol stock.