Anti-PSMC1 Antibody

Raised in rabbit against the 26S proteasome regulatory subunit PSMC1, this polyclonal antibody from Antibodies.com is supplied at 1 mg/ml in PBS containing 0.1% sodium azide and 50% glycerol as a cryoprotectant. The immunogen-derived reagent recognizes the ATPase ring subunit PSMC1, a core component of the 19S regulatory particle that drives ubiquitin-dependent protein turnover in eukaryotic cells. Validated for Western blot detection of the endogenous target in lysates prepared from human, mouse, and rat samples, the unconjugated reagent is appropriate for downstream immunodetection workflows including HRP- or fluorophore-coupled secondary labeling on nitrocellulose or PVDF membranes. The 100 µl vial format supports multiple probing experiments, and the glycerol-based buffer permits convenient storage at -20°C with minimal freeze-thaw handling between uses. Researchers studying proteasome function, protein homeostasis, and ATPase subunit biology will find this reagent useful for characterizing PSMC1 expression across mammalian model systems and for probing how 19S regulatory particle composition changes under proteotoxic stress.