Anti-PSMB5 Antibody

Raised in rabbits and supplied as an unconjugated polyclonal antiserum, this reagent targets PSMB5, the chymotrypsin-like catalytic beta subunit of the constitutive 20S proteasome core. PSMB5 contributes to intracellular protein turnover through the ubiquitin-proteasome pathway, and altered PSMB5 expression or mutation has been linked to bortezomib resistance in hematologic malignancy cells, supporting proteasome biology and chemoresistance research.

The antibody from Antibodies.com is validated for western blot, immunohistochemistry, and immunofluorescence workflows across human, mouse, and rat samples. Each vial contains 100 µl of the unconjugated antiserum, allowing flexible labelling with secondary conjugates of the researcher's choice. Storage at -20 °C in small working aliquots preserves activity across repeated freeze-thaw cycles and supports longer shelf life for ongoing projects.