Anti-PSMB1 Antibody

PSMB1 (Proteasome Subunit Beta type-1) is a β1 catalytic subunit of the 20S proteasome core, contributing to caspase-like peptidase activity that cleaves peptide bonds after acidic residues during ubiquitin-mediated protein degradation. This unconjugated rabbit polyclonal reagent from Antibodies.com detects the human PSMB1 protein and is supplied as 100 µl of antiserum. The antibody is validated for western blot detection of the ~23 kDa mature PSMB1 band, immunohistochemistry on formalin-fixed paraffin-embedded tissue sections, and immunofluorescence staining of cultured cells, supporting research into proteasome biology, MHC class I antigen presentation, NF-κB signaling, and protein turnover in cancer and neurodegeneration models. Polyclonal reactivity broadens epitope coverage for detecting denatured target in cell lysate preparations.