Anti-PSMB1 Antibody

This rabbit polyclonal antibody from Antibodies.com specifically targets PSMB1 (Proteasome 20S Subunit Beta 1), one of the catalytic beta subunits that form the inner beta-ring of the 20S proteasome core particle. As a central component of the ubiquitin-proteasome system, PSMB1 contributes to regulated intracellular protein degradation, making it a useful reagent for studies of proteostasis, cell-cycle progression, antigen processing, and cellular stress responses.

The reagent is supplied as a 100 µl liquid aliquot at 1 mg/ml in PBS containing 0.1% sodium azide as a preservative and 50% glycerol as a cryoprotectant, supporting stable storage and handling. It is unconjugated, allowing flexible pairing with secondary detection reagents of the researcher's choice, and shows reactivity against human, mouse, and rat samples, which supports cross-species experimental design.

Validated applications include Western blot (WB), immunohistochemistry (IHC), and immunofluorescence (IF), making the antibody applicable for confirming PSMB1 expression at the protein level across tissue sections, cultured cells, and lysate-based assays. Researchers working on proteasome subunit composition, proteasome inhibitor response, or comparative immunoproteasome studies can use this polyclonal reagent to detect the endogenous beta-1 subunit in standard immunoassays.