Anti-PSMA4 Antibody

Raised in rabbit against the proteasome subunit alpha type-4 (PSMA4), this unconjugated polyclonal antibody from Antibodies.com recognizes a core component of the 20S proteasome complex that participates in ubiquitin-dependent protein degradation. The reagent cross-reacts with human, mouse, and rat PSMA4 sequences, supporting comparative studies of proteasome assembly, cell cycle progression, and stress-response pathways across standard laboratory model organisms.

Validated for western blot, immunohistochemistry, and immunofluorescence workflows, the antibody is supplied as a 100 µL liquid aliquot in unconjugated form, ready for pairing with HRP-, biotin-, or fluorophore-conjugated secondary reagents. Typical experimental uses include profiling proteasome subunit composition in cancer cell lysates, examining proteasomal changes in neurodegenerative and muscle atrophy models, and localizing PSMA4 within subcellular compartments via immunostaining.

Aliquoting upon receipt and protection from light are recommended to preserve activity across multiple freeze-thaw cycles. Researchers should titrate the reagent for each application and detection system; the polyclonal format allows recognition of multiple epitopes on the target protein. The product is designated for research use only and is manufactured under quality-controlled conditions by Antibodies.com to support reproducible immunodetection in academic and industry laboratories.