Anti-PSMA4 Antibody

PSMA4 is a 20S proteasome alpha subunit (gene symbol PSMA4), essential to ubiquitin-mediated protein degradation in eukaryotic cells. This Antibodies.com rabbit polyclonal reagent binds the endogenous protein across multiple model systems, supporting western blot detection of proteasomal complexes, immunohistochemistry localization in tissue sections, and immunofluorescence imaging of subcellular distribution. The antibody was raised in rabbit and purified to 1 mg/ml in PBS with 0.1% sodium azide and 50% glycerol as a cryoprotectant, supplied as a 100 µl vial suitable for multiple experimental rounds.

Validated for reactivity with human, mouse, and rat samples, the unconjugated format lets researchers pair it with their preferred secondary antibody or custom label. Common research applications include studies of proteasome assembly, investigations of proteasome inhibition in cancer and neurodegeneration models, profiling of proteolytic activity regulators, and characterization of MHC class I antigen-processing pathways. Storage at -20 °C in working aliquots is recommended to preserve activity across freeze-thaw cycles, and the glycerol-containing buffer helps maintain antibody stability during routine handling.