Anti-PSMA2 Antibody

PSMA2 is one of seven alpha-type subunits that form the outer ring of the 20S proteasome core particle, where it contributes to the gated channel that controls entry of ubiquitinated substrates into the catalytic chamber. This rabbit polyclonal reagent from Antibodies.com is raised against the human PSMA2 protein and supplied as 100 µL of unconjugated antiserum in a single vial, ready for dilution in standard PBS-based buffers. The antibody detects the endogenous human antigen in cell and tissue preparations and is validated for western blot, immunohistochemistry, and immunofluorescence workflows, supporting studies of proteasome assembly, ubiquitin-dependent protein turnover, and altered proteasomal activity in cancer cell biology and neurodegenerative disease models. Researchers can apply the polyclonal format to maximise recognition of multiple epitopes within PSMA2, which is useful when monitoring subunit incorporation into nascent proteasome complexes or probing changes in proteasome composition under pharmacological inhibition. The unconjugated format is compatible with both chemiluminescent and fluorescence secondary detection chemistries, and each vial is intended for research use only.