Anti-PSIP1 Antibody

Rabbit polyclonal antibody targeting PSIP1 (PC4 and SFRS1 Interacting Protein 1), also known as LEDGF/p75 or the DFS70 autoantigen, supplied by Antibodies.com as a 100 µl vial of unconjugated IgG for western blot applications. The reagent recognizes endogenous PSIP1 across human, mouse, and rat samples, making it a useful tool for studies of transcriptional coactivation, chromatin tethering, and stress-response signaling in which the LEDGF/p75 splice isoform participates. Researchers investigating HIV-1 integrase cofactor function, autoimmune dense-fine-speckled immunofluorescence patterns, or lens-epithelium-derived growth factor activity have used this antibody to detect the ~75 kDa band in cell lysates. The polyclonal mixture is produced in rabbit and provided unconjugated, allowing flexible pairing with HRP or fluorophore-conjugated secondary reagents of the researcher's choice. Aliquot upon receipt and store refrigerated; repeated freeze-thaw cycles should be avoided to preserve antibody activity.