Anti-PSAT1 Antibody - Identical to Abcam (ab96136)

This polyclonal antibody from Antibodies.com targets human phosphoserine aminotransferase 1 (PSAT1), a 40 kDa enzyme of the serine biosynthesis pathway that catalyzes the transamination of 3-phosphohydroxypyruvate to phosphoserine. Raised in rabbit and supplied unconjugated in a 100 µl vial, the reagent is validated for western blot, immunohistochemistry, and immunofluorescence workflows, supporting studies of one-carbon metabolism and tumor cell metabolic reprogramming.

PSAT1 sits at a branch point feeding glycine and downstream folate-cycle intermediates, and it has been investigated in the context of breast, lung, and colorectal carcinoma, where elevated expression correlates with proliferation and poor prognosis. Researchers use the antibody to map expression across tissue microarrays, confirm CRISPR or RNAi knock-downs by immunoblot, and visualize subcellular distribution by confocal imaging, since the endogenous protein localizes to the cytosol.

The preparation should be frozen and stored at -20 °C in working-size aliquots to limit repeated freeze-thaw cycling of the stock. It corresponds to Abcam ab96136, providing an independent source for laboratories standardizing on that reference reagent. For research use only.