Anti-PSAT1 Antibody

This unconjugated rabbit polyclonal antibody from Antibodies.com targets PSAT1 (phosphoserine aminotransferase 1), a key enzyme in the L-serine biosynthesis pathway that has emerged as a focus of cancer metabolism research. Raised in rabbit and supplied at 100 µl, the reagent is validated for Western blot and immunofluorescence workflows on human samples, making it well suited to studies of serine pathway regulation in tumor cell lines and tissue specimens.

PSAT1 catalyzes the conversion of 3-phosphohydroxypyruvate to 3-phosphoserine and is frequently overexpressed in breast, colorectal, and non-small cell lung cancers, where elevated levels correlate with proliferative and metastatic phenotypes. Researchers use this reagent to probe expression patterns, subcellular localization, and pathway activity under conditions such as nutrient deprivation, hypoxia, or pharmacological inhibition. The polyclonal format provides recognition of multiple epitopes on the target, which can be advantageous when detecting isoform variants or working with samples where epitope accessibility may vary.

Aliquot upon receipt and store refrigerated to preserve activity across repeated experiments; protect from light to maintain reagent stability. For research use only.