Anti-PSAT1 Antibody

The PSAT1 antibody from Antibodies.com is a rabbit polyclonal reagent raised against phosphoserine aminotransferase 1, a cytoplasmic enzyme in the L-serine biosynthesis pathway that branches from glycolysis via 3-phosphoglycerate. The unconjugated antibody is supplied as a 100 µl vial at 1 mg/ml in PBS with 0.1% sodium azide and 50% glycerol, a buffer formulation that already incorporates a cryoprotectant for low-temperature storage. Researchers use this reagent in western blot and immunohistochemistry experiments to examine PSAT1 expression in human, mouse, and rat samples, supporting studies of one-carbon metabolism, nucleotide biosynthesis, and the metabolic rewiring seen in tumor cells where PSAT1 is frequently overexpressed. For handling, aliquots should be kept at -20°C to limit freeze-thaw damage, and the glycerol in the formulation helps preserve activity across freeze-thaw cycles. The polyclonal format offers recognition of multiple epitopes on PSAT1, which is useful when probing protein levels across varying cancer models including breast, lung, and colorectal tissue, as well as for IHC analysis of formalin-fixed paraffin-embedded sections to localize the enzyme in situ. This primary antibody is intended for research use only and is provided unconjugated for flexibility with secondary detection reagents and custom labeling workflows.