Anti-PRX III Antibody

Supplied as 100 µl of unconjugated rabbit antiserum, this polyclonal antibody from Antibodies.com selectively detects Peroxiredoxin 3 (PRX III), a mitochondrially localized thioredoxin-dependent antioxidant peroxidase responsible for scavenging hydrogen peroxide and organic hydroperoxides through a reactive cysteine catalytic cycle. The reagent was raised against an epitope conserved in human, mouse, and rat PRX III, enabling translational work that compares rodent disease models with patient-derived material. Validated applications include Western blot, immunohistochemistry, and ELISA, covering use cases such as confirming knockdown or overexpression in cultured cell lines, mapping tissue distribution in IHC sections, and quantitative antigen detection. For storage, aliquot upon arrival and store frozen at -20 °C, limiting repeated freeze-thaw cycles to preserve binding activity and protect the reagent from prolonged light exposure.