Anti-PRPF39 Antibody

PRPF39 (Pre-mRNA Processing Factor 39) is a spliceosomal protein that participates in U4/U6.U5 tri-snRNP assembly and catalytic activation of the spliceosome. This polyclonal antibody from Antibodies.com is raised in rabbit and specifically recognizes the human PRPF39 target, supporting research into RNA splicing mechanisms, spliceosome composition, and post-transcriptional gene regulation.

Validated for Western blot (WB) and immunohistochemistry (IHC) applications, the antibody is supplied as an unconjugated reagent in a 100 µl volume, allowing flexible protocol optimization including custom secondary antibody pairing and signal amplification strategies. Its reactivity with human samples makes it relevant to studies involving cultured cell lines and tissue specimens aimed at characterizing splicing factor expression.

PRPF39 has been linked to alternative splicing events and reported in investigations of spliceosome dysregulation, including work in hepatocellular carcinoma and other tumor types where aberrant RNA processing contributes to disease phenotypes. Researchers studying mRNA processing, ribonucleoprotein complex assembly, or the molecular consequences of splicing factor perturbation may use this reagent to detect endogenous PRPF39 expression patterns across experimental systems.