Anti-PRPF31 Antibody

This 100 µl, unconjugated rabbit polyclonal IgG reagent from Antibodies.com is listed for use in western blot (WB) detection of human PRPF31. Because it is supplied without a fluorophore or enzyme label, researchers can pair it with a compatible labeled secondary antibody and the detection system best suited to their membrane and imaging workflow.

PRPF31 is a spliceosomal protein associated with the U4/U6-U5 tri-small nuclear ribonucleoprotein complex, which participates in pre-mRNA processing and spliceosome assembly. The target is relevant to studies of RNA-splicing regulation and gene-expression control. Human variants in PRPF31 are associated with autosomal dominant retinitis pigmentosa, making the protein relevant to mechanistic and expression research in appropriate cell models.

The antibody can be incorporated into immunoblot workflows using prepared human protein samples, with loading controls and appropriate positive and negative controls. The unconjugated primary reagent does not include a detection kit, membrane, blocking buffer, secondary antibody, or imaging substrate; those components must be selected separately. Human is the listed reactive species, while mouse and rat reactivity are not listed and should not be inferred from the available product information. Store and handle the reagent according to the current product documentation.