Anti-PRP4K Antibody

PRP4K, also known as PRPF4B, is a serine/threonine kinase that associates with the U4/U6.U5 tri-snRNP complex of the spliceosome and phosphorylates components such as PRP6 to drive catalytic activation of pre-mRNA splicing. The kinase has additional roles in DNA damage checkpoint signaling and mitotic progression, linking RNA processing to cell cycle control and genome stability. This polyclonal reagent from Antibodies.com is raised in rabbit against PRP4K, reacts with human samples, and is validated for Western blot and immunofluorescence. Supplied unconjugated in a 100 µl volume, the antibody supports detection of endogenous PRP4K in cell lysates and visualization of its subcellular distribution in fixed cells, making it useful for research in spliceosome biochemistry, splicing-factor regulation, and cancer signaling contexts where PRP4K activity has been investigated.