Anti-Protocadherin 16 Antibody

The antibody recognizes Protocadherin 16 (PCDH16), also designated DCHS1, a calcium-dependent cell adhesion protein belonging to the cadherin superfamily. DCHS1 contributes to planar cell polarity signaling during embryonic development and is notable for its role in cardiac morphogenesis; loss-of-function variants in the encoding gene have been associated with mitral valve prolapse, periventricular heterotopia, and Van Maldergem syndrome.

Provided by Antibodies.com as an unconjugated polyclonal reagent in liquid form, this antibody is validated for western blot and immunocytochemistry on human samples. Store at -20 degrees C in single-use aliquots to preserve activity across multiple freeze-thaw cycles; working dilutions may be kept refrigerated for short-term use. Researchers in cardiac developmental biology, hearing research (DCHS1 also participates in inner ear patterning), and connective tissue disorders may use this reagent for expression profiling and co-localization studies.