Anti-Progesterone Receptor (Ab-190) Antibody

The polyclonal antibody supplied by Antibodies.com is raised in rabbit and recognizes a defined epitope of the human progesterone receptor (PR), a nuclear steroid hormone receptor that mediates progesterone signaling in reproductive tissues and serves as a clinically important biomarker in breast cancer pathology.

Supplied as a 100 µl liquid aliquot of unconjugated immunoglobulin, the reagent is validated for Western blot (WB) and immunofluorescence (IF) workflows on human samples, supporting laboratories studying hormone-responsive gene regulation, mammary tumor biology, and endometrial function.

As a research-grade primary antibody for progesterone receptor status assessment, it enables investigation of estrogen and progesterone receptor co-expression patterns in breast carcinoma specimens and can be paired with standard HRP-conjugated or fluorescently labeled secondary reagents for chromogenic or fluorescence imaging of fixed cells and tissue sections.

For best results, the antibody should be stored refrigerated and aliquoted to limit repeated freeze-thaw cycles, while its polyclonal nature provides recognition of multiple epitopes across the receptor — useful when probing for truncated PR isoforms or variant receptor populations in cell lysate preparations from hormone-responsive cell lines.