Anti-Proactivator polypeptide Antibody

Raised in rabbits and affinity-purified, this polyclonal antibody targets the proactivator polypeptide, the precursor protein that gives rise to saposins A, B, C, and D, the lysosomal cofactors required for sphingolipid catabolism. Distributed by Antibodies.com, the reagent is validated for Western blot (WB) and immunohistochemistry (IHC) workflows on human samples and is supplied unconjugated at 100 µg per vial. Researchers investigating lysosomal storage disorders — including Gaucher disease, metachromatic leukodystrophy, and Krabbe disease — use proactivator polypeptide detection to map saposin expression across tissue sections and protein lysates. The polyclonal format broadens epitope coverage relative to monoclonal alternatives, which is useful when probing processed fragments or post-translationally modified intermediates of prosaposin. For long-term storage, aliquot and freeze at –20 °C and avoid repeated freeze-thaw cycles to preserve antibody activity.