Anti-PRMT6 Antibody

This Mouse monoclonal IgG1 primary antibody from Antibodies.com targets PRMT6 (Protein Arginine Methyltransferase 6), a nuclear type I arginine methyltransferase that catalyzes asymmetric dimethylation of histone H3 at arginine 2. Supplied as 100 µl of unconjugated reagent, the antibody is validated for western blot, immunocytochemistry, and immunohistochemistry applications on human, mouse, and rat samples.

PRMT6 has been characterized as an epigenetic regulator with roles in transcriptional control, the cellular DNA damage response, and modulation of steroid-receptor signaling pathways, including estrogen receptor and androgen receptor activity. Researchers use this reagent to investigate histone arginine methylation marks, post-translational modification of non-histone substrates, and chromatin-associated changes in fixed cells, frozen or paraffin-embedded tissue sections, and whole-cell lysates. For routine work, keep refrigerated and aliquot on arrival to limit freeze-thaw cycles and preserve binding activity across repeated experiments.