Anti-PRMT6 Antibody

Protein Arginine Methyltransferase 6 (PRMT6) is a type I arginine methyltransferase that catalyzes asymmetric dimethylation of arginine residues on histone and non-histone substrates, influencing transcription regulation, RNA splicing, and the DNA damage response. This mouse monoclonal reagent from Antibodies.com detects the human PRMT6 protein in western blot, immunohistochemistry, and immunocytochemistry workflows, supporting research in epigenetics, chromatin biology, and oncology where PRMT6 activity has been connected to tumor suppressor pathways and to methylation of viral proteins such as HIV-1 Tat.

Supplied as a 100 µl volume of purified immunoglobulin in 0.1 M Tris-Glycine buffer (pH 7.4) with 150 mM NaCl, 0.2% sodium azide, and 50% glycerol, the unconjugated antibody can be paired with user-selected reporter chemistries. Endogenous PRMT6 can be resolved from cultured human cell lines and visualized in fixed tissue sections, enabling investigation of histone H3R2 asymmetric dimethylation marks and other PRMT6-dependent substrate modifications.